
Vaccinate yourself against your own tumor
Vaccinate yourself against your own tumor to train your body to proactively protect against recurrence
The cancer vaccine field has yet to become a systematic science despite decades of work and a steadily rising number of clinical trials since the first clinical PoC a decade ago.
In its Phase II readout, Moderna’s mRNA-4157 therapy in combination with Keytruda significantly improved outcomes for patients with resected stage III/IV melanoma. However, even that study has major caveats.
The Field’s Stumbling Blocks
We at Compound are excited about more comprehensive assays (full genome sequencing, more relevant readout, etc), novel target spaces & manufacturing leaps
https://www.modernatx.com/en-US
https://www.biontech.com/int/en/home.html
Infinitopes https://www.infinitopes.com/
https://www.mackenziemorehead.com/the-failures-and-futures-of-cancer-vaccines/