CompoundThesisDatabase

Self-amplifying drugs

Increase potency, decrease COGS

2nd Life Batteries for Storage

Used EV batteries repurposed for grid and data center energy storage

Marketplaces Requiring Private Intelligence

For deals requiring human-like analysis and negotiation but can’t risk information leakage

Onchain Options

onchain options

New bio data + AI businesses

Full-stack business required when new data modalities come online

Distributed Water Desalination

Solving the water problem with distributed systems

Ozempic for Sleep

A sleep-focused therapeutics startup

Personalized organoid aging

Longevity Intervention Testing

Going direct with diagnostics

Rise of consumer Tempus models

AI-ification of R&D proteins

Better, faster, cheaper antibodies and enzymes

Robots Built for Wonder

If Disney and Dyson were started today

Cancer Vaccines

Vaccinate yourself against your own tumor

Autonomous surgeries

Scaling safe and effective procedures

Cross-Company Agent Layer

Cross-Company Agent Layer

Venoms, poisons, stings

Computation drug discovery for long-tail of diseases

Robot Insurance

Protecting against malfunction

Formal Verification at Scale

Making software vulnerabilities a thing of the past

Government Modernization

How to make gov cutting edge

Distraction-Free Personal Device

Minimally viable, distraction-freeing personal device

Computable Contracts

Autonomous execution of legal and commercial contracts

Cancer prevention drugs

Exposome

Environment-encompassing health

Biosurveillance via mosquito sequencing

New data collection needed

Digital Identity

Somehow no one’s cracked it yet

Decentralized Debt Clearing

Clearing houses open to anyone

Decentralized Undercollateralized Lending

Making crypto lending an order of magnitude more capital efficient and able to fund non-speculative development

Scarce AI Models

Bringing specificity and uniqueness to AI models

Biochemical Wearables, Ingestibles, Implantables

In between a FitBit and CAR-T therapy

Protein sequencing

Technical unlock to protein-wide understanding

A therapeutic biomining platform of parasites

A ripe chemical space

Self-driving Labs

No more pipetting!

Taste Engineering

Next culinary frontier

Biobanks

Trojan horse diagnostics to get massive patient data

Interfaces for neuromodulation

Closing the loop from measurement → action

Decentralized Wearables

Health (data) Is Wealth

Neural Net Potentials

Simulating complex physical processes at atomic accuracy and practical speed

Retail Robotics

Multi-use robots for retail environments

Acoustic Sensor Network

Scaling audio-based security in a privacy-centric way

Just-In-Time Liquidity

Liquidity when you need it, and not a moment too soon

Next-generation organ replacements

Hybrid animals

Decentralized Economically Important Data Gathering Protocol

Premise Data, Decentralized

Decentralized Content Delivery Networks

It’s my content and I want it NOW

Leveraged Prediction Markets

Prediction markets, but make it fun

Novel Security & Authentication

Novel authentication in an advanced computing and interconnected world

Biotech for endangered species

save the koalas

LVMH for bio

biotech but pretty

Platforms for SOTA sequencing experimentation and analysis

made for experts not nubes

In vivo detoxification

part of a healthy living

Decentralized Energy Grids

Democratizing and Digitizing Energy

Local Compute & Personal Cloud Computing

Enabling the in-home compute stack

Delaying menopause

This is part of longevity

Rewarding biosampling

Incentivizing the collection of bio data

Iconiq For Crypto

Full-service wealth management

‘Human’ in a test tube

Recapitulating the microenvironment to increase the predictive validity of cell culture

Biohacking

Taking control of our bodies and world

Bio in Space

More biology manufacturing and research facilities will be extraterrestrial

“Smarter” Yield-Seeking Contracts

Dynamic, active yield-seeking strategies for passive participants

Unlocking Underutilized Assets With Distributed Networks

Tapping into idle assets through distributed networks

“Real” Work in Crypto

IRL activity allowing users to earn tokens in an on-chain network

The rise of OTC and off-label medication

Broadening access to medicines + new modalities

Next Generation Game Engines and Infrastructure

Game engine technology will seep into general software primitives

DNA Synthesis

Ripe for engineering step-change.

Nanomedicines, neomarkets

Working inside and outside traditional drug discovery

Psychedelic medicine

Opportunities in a crowded space

Data brokers in biotech

Secure, anonymized biological data transfer

Future of Family Planning (Horizontal Thesis)

New clinical models, digital health models, and biology for tackling family planning

Computational Creativity (Horizontal Thesis)

Utilizing machine learning to scale creativity

AI-Enabled Medical Devices

More advanced and precise medical devices, enabled by AI/ML

Modified Humans (Horizontal Thesis)

A look at how humans are going to be continually biologically and mechanically modified, treated, and selected.

In-Space Data Centers

Data Centers…but in space

Pediatric Care

Tia for Children (with mental health included)

Science Driven Mental Health

A deeper understanding of biomarkers for mental health

Smart Toilets

Connected toilets to monitor waste and deliver insights

Projection Mapping

Headsetless Immersive Computing

Adversarial Attacks on ML Models

Defending machine learning and computer vision

Self-Sufficient Utilities in a box

Pod for going off-grid for residential homes

Financial Data Querying via LLMs

Bloomberg + Tableau with LLMs

LLM Centric Search Engine

Utilizing large models for better, narrow search experiences

Product vs. platform synthetic biomanufacturing

Field is headed back to platform and enabling platforms

Cybersecurity for On-Chain

Protecting crypto users and protocols

Executive Assistant Software

Software for Executive Assistants

Novel Multi-Sig Protocol

Fork Gnosis and make multi-sig better UI/UX

Expanding endometriosis

Businesses need to look towards other indications.

Crayon for Crypto

Competitive Intelligence Tool for On-Chain Orgs/DAOs

Audio for early detection of defects or diseases

Utilizing on-human and on-environment audio cues for early detection of health diseases or defects.

Knowledge Management tools for Doctors and Healthcare

Notion for Doctors

Federated Learning

Privacy-preserving machine learning models for privacy sensitive industries

In-Home Robotics

Robotics, in the home.

Polypharmacology & Drug Data Repurposing

CRISPR knockouts to help us understand complex relationships between drug targets

The recalibration phase of AI in drug discovery

What we need to do to see the promise of AI in drug discovery

Bioinformatics Software

Data workflows in biology labs will become more streamlined as mainstream software is adopted and network affects kick in

Continuous Hormone Monitoring + Auto-Immunity Management

Digital health for endocrinology

D2C Diagnostic Testing for Pets

At home diagnostics for large categories of pet issues that enable expansion into retail recommendations

Battery Recycling

Tertiary businesses around recycling the incoming wave of EV batteries for things such as raw materials or on-grid storage.

Future of education

New models for education: supplementary accredited courses, D2C & remedial

Food as Medicine

Targeted nutrient deprivation therapies for cancer

Advanced Treasury Diversification/Management

Diversifying DAO Treasuries

VR as a Desktop Computing Replacement

No more monitors

Functional readouts in diagnostics - TCR

Clinic needs to catch up with the research

Robotics for Recycling

Robotic trash and recycling sorting.