Compound
GrantsAbout

2026 Compound

Compound
GrantsAbout
Back to Database
Nanomedicines, neomarkets
Healthcare

Nanomedicines, neomarkets

Working inside and outside traditional drug discovery

Bio

Concept

Nanomedicines could replace therapeutic antibodies (Debesh) or be used as a preventative against viral or bacterial infections.

Longer Description

I’ve previously discussed the new types of businesses being built in biology. One of the segments I highlighted were nanomedicines, which are able to reduce viral transmission of COVID and STI’s. However, their prominence is increasing with expanded technologies and use-cases. With this article, I plan to cover the main types of nanomedicines, their current status, and future potential.

Nanomedicine is the technology that is underpinning RNA and DNA therapeutics and vaccines by allowing for the cargo delivery to a certain cell type. The most common use case of nanomedicines is in drug delivery, primarily through lipid nanoparticles or liposomes. (Exosomes are also of interest but harder to generate due to the our reliance on cells to produce exosomes).

Other thoughts

  • GTM will depend on functionality but a B2C or regulation-light market access approach would allow for separate revenue streams while functionality is built out.
  • With each new nanomedicine comes with its special ADMET profile which will need to be tested rigorously. Liver accumulation specifically will need to be addressed.

Comparable Companies

  • Cellics Therapeutics
  • Atom Bioworks
  • Nanograb

Related Reading

  • https://www.sciencedirect.com/science/article/pii/S0753332220312968
  • https://www.pennmedicine.org/news/news-releases/2022/january/penn-medicine-researchers-develop-new-method-to-increase-effectiveness-of-nanomedicines

Related Theses

Self-amplifying drugs
01
Bio

Self-amplifying drugs

Increase potency, decrease COGS

Read
Marketplaces Requiring Private Intelligence
02
AI/ML

Marketplaces Requiring Private Intelligence

For deals requiring human-like analysis and negotiation but can’t risk information leakage

Read
New bio data + AI businesses
03
Bio

New bio data + AI businesses

Full-stack business required when new data modalities come online

Read

2026 Compound